Life Science Buffers

Balanced salt solutions and powders used for molecular, protein, nucleic acid, and cell biology applications including cell culture, electrophoresis, ELISA, and chromatography processes; available in a variety of formulations and grades.

Buffer solutions serve to keep pH (acidity or alkalinity) nearly constant in a variety of chemical and biological applications. For example, a bicarbonate buffer helps maintain the pH of blood, a buffered saline maintains cellular contents at a consistent pH level, and buffers help maintain a narrow pH range for enzymes to function correctly.

Most biological samples used in research are kept at a pH of about 7.4. Common biological buffers used for tissue culture include Dulbeccos phosphate buffered saline (PBS), Tris base, HEPES, MOPS, PIPES, and other formulations developed for specific cell lines or applications. Most buffers used in cell culture are also DNase-, RNase-, and protease-free.

The choice of buffer for a particular biological reaction or site depends on several factors:

Temperature
Desired or target pH
Buffer toxicity (to the system)
Buffer interactions with other system components

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421 – 435 of 3,492 results

421

Tris-Borate-EDTA Buffer, MP Biomedicals™

MDL Number: MFCD00236358 Synonym: TBE buffer

Pricing & Availability
Specifications

MDL Number	MFCD00236358
Synonym	TBE buffer

422

TrisHydroxymethyl)Aminomethane ACS AR, Macron Fine Chemicals™

CAS: 77-86-1 Molecular Formula: C4H11NO3 Molecular Weight (g/mol): 121.136 InChI Key: LENZDBCJOHFCAS-UHFFFAOYSA-N PubChem CID: 6503 ChEBI: CHEBI:9754 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol SMILES: C(C(CO)(CO)N)O

Pricing & Availability
Specifications

PubChem CID	6503
CAS	77-86-1
Molecular Weight (g/mol)	121.136
ChEBI	CHEBI:9754
SMILES	C(C(CO)(CO)N)O
IUPAC Name	2-amino-2-(hydroxymethyl)propane-1,3-diol
InChI Key	LENZDBCJOHFCAS-UHFFFAOYSA-N
Molecular Formula	C4H11NO3

423

MP Biomedicals™ 1X Hanks' Balanced Salt Solution, Modified

Red, Clear Solution

Pricing & Availability

424

Tris Hydrochloride, >99%, Reagent grade, MP Biomedicals™

CAS: 1185-53-1 Molecular Formula: C4H12ClNO3 Molecular Weight (g/mol): 157.594 MDL Number: MFCD00012590 InChI Key: QKNYBSVHEMOAJP-UHFFFAOYSA-N Synonym: Trometamol,Tromethamine PubChem CID: 93573 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride SMILES: C(C(CO)(CO)N)O.Cl

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Specifications

PubChem CID	93573
CAS	1185-53-1
Molecular Weight (g/mol)	157.594
MDL Number	MFCD00012590
SMILES	C(C(CO)(CO)N)O.Cl
Synonym	Trometamol,Tromethamine
IUPAC Name	2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride
InChI Key	QKNYBSVHEMOAJP-UHFFFAOYSA-N
Molecular Formula	C4H12ClNO3

425

MilliporeSigma™ PIPES, Sodium Salt, Molecular biology grade, OmniPur™, Calbiochem™,

CAS: 100037-69-2 Molecular Formula: C16H33N4Na3O12S4 Molecular Weight (g/mol): 670.665 InChI Key: FPDACHMSOMILQI-UHFFFAOYSA-K PubChem CID: 3086462 IUPAC Name: trisodium;2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonate;2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonate SMILES: C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)[O-].C1CN(CCN1CCS(=O)(=O)[O-])CCS(=O)(=O)[O-].[Na+].[Na+].[Na+]

Pricing & Availability
Specifications

PubChem CID	3086462
CAS	100037-69-2
Molecular Weight (g/mol)	670.665
SMILES	C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)[O-].C1CN(CCN1CCS(=O)(=O)[O-])CCS(=O)(=O)[O-].[Na+].[Na+].[Na+]
IUPAC Name	trisodium;2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonate;2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonate
InChI Key	FPDACHMSOMILQI-UHFFFAOYSA-K
Molecular Formula	C16H33N4Na3O12S4

426

Promotions Available

PIPES, disodium salt, 99%

CAS: 76836-02-7 Molecular Formula: C8H16N2Na2O6S2 Molecular Weight (g/mol): 346.324 InChI Key: GMHSTJRPSVFLMT-UHFFFAOYSA-L Synonym: 1, 4-Piperazinediethanesulfonic acid disodium salt PubChem CID: 173553 ChEBI: CHEBI:63055 IUPAC Name: disodium;2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonate SMILES: C1CN(CCN1CCS(=O)(=O)[O-])CCS(=O)(=O)[O-].[Na+].[Na+]

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Specifications

PubChem CID	173553
CAS	76836-02-7
Molecular Weight (g/mol)	346.324
ChEBI	CHEBI:63055
SMILES	C1CN(CCN1CCS(=O)(=O)[O-])CCS(=O)(=O)[O-].[Na+].[Na+]
Synonym	1, 4-Piperazinediethanesulfonic acid disodium salt
IUPAC Name	disodium;2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonate
InChI Key	GMHSTJRPSVFLMT-UHFFFAOYSA-L
Molecular Formula	C8H16N2Na2O6S2

427

MilliporeSigma™ MOPS, Sodium, ULTROL™ Grade, Calbiochem™,

CAS: 71119-22-7 Molecular Formula: C7H14NNaO4S Molecular Weight (g/mol): 231.242 InChI Key: MWEMXEWFLIDTSJ-UHFFFAOYSA-M Synonym: 3-(N-Morpholino)propanesulfonic Acid, Na PubChem CID: 3859613 IUPAC Name: sodium;3-morpholin-4-ylpropane-1-sulfonate SMILES: C1COCCN1CCCS(=O)(=O)[O-].[Na+]

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Specifications

PubChem CID	3859613
CAS	71119-22-7
Molecular Weight (g/mol)	231.242
SMILES	C1COCCN1CCCS(=O)(=O)[O-].[Na+]
Synonym	3-(N-Morpholino)propanesulfonic Acid, Na
IUPAC Name	sodium;3-morpholin-4-ylpropane-1-sulfonate
InChI Key	MWEMXEWFLIDTSJ-UHFFFAOYSA-M
Molecular Formula	C7H14NNaO4S

428

MilliporeSigma™ Guanidine Thiocyanate, ≥99%, Calbiochem™,

CAS: 593-84-0 Molecular Formula: CH₅N₃ · CHNS

Pricing & Availability
Specifications

CAS	593-84-0
Molecular Formula	CH₅N₃ · CHNS

429

R&D Systems™ PBS Tablets

A Novus product, part of R&D Systems. Phosphate buffered saline tablets pH 7.4

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430

MilliporeSigma™ Tris, Hydrochloride, ULTROL™ Grade, Calbiochem™,

CAS: 1185-53-1 Molecular Formula: C4H12ClNO3 Molecular Weight (g/mol): 157.594 InChI Key: QKNYBSVHEMOAJP-UHFFFAOYSA-N Synonym: tris(Hydroxymethyl)aminomethane, HCl PubChem CID: 93573 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride SMILES: C(C(CO)(CO)N)O.Cl

Pricing & Availability
Specifications

PubChem CID	93573
CAS	1185-53-1
Molecular Weight (g/mol)	157.594
SMILES	C(C(CO)(CO)N)O.Cl
Synonym	tris(Hydroxymethyl)aminomethane, HCl
IUPAC Name	2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride
InChI Key	QKNYBSVHEMOAJP-UHFFFAOYSA-N
Molecular Formula	C4H12ClNO3

431

Thermo Scientific Chemicals TBE urea sample buffer (2X)

Pricing & Availability
Specifications

Color	Blue
Physical Form	Liquid
Chemical Name or Material	Sample Loading Buffer
Concentration	2X

432

MOPSO, 99.5%, MP Biomedicals™

CAS: 79803-73-9 Molecular Formula: C7H14NNaO5S Molecular Weight (g/mol): 247.241 InChI Key: WSFQLUVWDKCYSW-UHFFFAOYSA-M Synonym: sodium 2-hydroxy-3-morpholinopropane-1-sulfonate,mopso sodium salt,3-morpholino-2-hydroxypropanesulfonic acid sodium salt,3-n-morpholinyl-2-hydroxypropanesulfonic acid sodium salt,sodium 2-hydroxy-3-morpholin-4-yl propane-1-sulfonate,mopso sodium salt titration,mopso, 0.2m buffer solution, ph 6.0,mopso, 0.2m buffer solution, ph 6.5,mopso, 0.2m buffer solution, ph 7.0,mopso, 0.2m buffer solution, ph 7.5 IUPAC Name: sodium;2-hydroxy-3-morpholin-4-ylpropane-1-sulfonate

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Specifications

CAS	79803-73-9
Molecular Weight (g/mol)	247.241
Synonym	sodium 2-hydroxy-3-morpholinopropane-1-sulfonate,mopso sodium salt,3-morpholino-2-hydroxypropanesulfonic acid sodium salt,3-n-morpholinyl-2-hydroxypropanesulfonic acid sodium salt,sodium 2-hydroxy-3-morpholin-4-yl propane-1-sulfonate,mopso sodium salt titration,mopso, 0.2m buffer solution, ph 6.0,mopso, 0.2m buffer solution, ph 6.5,mopso, 0.2m buffer solution, ph 7.0,mopso, 0.2m buffer solution, ph 7.5
IUPAC Name	sodium;2-hydroxy-3-morpholin-4-ylpropane-1-sulfonate
InChI Key	WSFQLUVWDKCYSW-UHFFFAOYSA-M
Molecular Formula	C7H14NNaO5S

433

ADA, 0.2M buffer soln., pH 6.5, Thermo Scientific™

CAS: 7415-22-7 Molecular Formula: C6H9N2NaO5 Molecular Weight (g/mol): 212.137 MDL Number: MFCD00065483 InChI Key: QCGKKVWCABJQQI-UHFFFAOYSA-M PubChem CID: 23679048 IUPAC Name: sodium;2-[(2-amino-2-oxoethyl)-(carboxymethyl)amino]acetate SMILES: C(C(=O)N)N(CC(=O)O)CC(=O)[O-].[Na+]

Pricing & Availability
Specifications

PubChem CID	23679048
CAS	7415-22-7
Molecular Weight (g/mol)	212.137
MDL Number	MFCD00065483
SMILES	C(C(=O)N)N(CC(=O)O)CC(=O)[O-].[Na+]
IUPAC Name	sodium;2-[(2-amino-2-oxoethyl)-(carboxymethyl)amino]acetate
InChI Key	QCGKKVWCABJQQI-UHFFFAOYSA-M
Molecular Formula	C6H9N2NaO5

434

Thermo Scientific Chemicals HEPES-buffered saline, pH 6.5 (5X)

CAS: 7365-45-9 Molecular Formula: C8H18N2O4S Molecular Weight (g/mol): 238.30 MDL Number: MFCD00006158 InChI Key: JKMHFZQWWAIEOD-UHFFFAOYSA-N PubChem CID: 23831 ChEBI: CHEBI:42334 IUPAC Name: 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid SMILES: OCCN1CCN(CCS(O)(=O)=O)CC1

Pricing & Availability
Specifications

PubChem CID	23831
CAS	7365-45-9
Molecular Weight (g/mol)	238.30
ChEBI	CHEBI:42334
MDL Number	MFCD00006158
SMILES	OCCN1CCN(CCS(O)(=O)=O)CC1
IUPAC Name	2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
InChI Key	JKMHFZQWWAIEOD-UHFFFAOYSA-N
Molecular Formula	C8H18N2O4S

435

MilliporeSigma™ Sodium Salt, Pipes, OmniPur™, Calbiochem™,

Pricing & Availability
Specifications

PubChem CID	3086462
CAS	100037-69-2
Molecular Weight (g/mol)	670.665
SMILES	C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)[O-].C1CN(CCN1CCS(=O)(=O)[O-])CCS(=O)(=O)[O-].[Na+].[Na+].[Na+]
IUPAC Name	trisodium;2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonate;2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonate
InChI Key	FPDACHMSOMILQI-UHFFFAOYSA-K
Molecular Formula	C16H33N4Na3O12S4

Life Science Buffers

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